Background: Patients with mandibular incisors agenesis often seek treatment to address both aesthetic and functional concerns. The clinical examination and management for these patients may differ from our standard diagnosis and treatment planning protocols.

Objective: This article aimed to collect and review relevant literatures, discussing the necessity for specific attention to the quantity and location of missing mandibular incisors.

Method and results: An electronic literature search was conducted in PubMed and the Cochrane Central Library, focusing on specific objectives. Relevant articles were identified, resulting in a total of 64 articles after duplicates and irrelevant sources were removed.

Discussion and conclusion: Given the diverse nature of the malocclusions observed in patients, there are no universally applicable standard protocols. Tailored management strategies, such as space creation for prosthetic placement or space closure, should be determined on a case-by-case basis to optimize aesthetics, functionality, and stability. Considerations such as Bolton discrepancy, interproximal reduction, prosthetic replacement options, tooth substitution (such as canine to lateral and premolar to canine teeth), bracket prescription, anchorage planning, gingival and periodontal health, and retention planning are all critical factors influencing successful outcomes.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.